- Build muscle and/or enhance athletic performance.
- Complement his or her current athletic supplement stack.
- Promote muscle growth while avoiding androgen supplements (e.g. women).
Anabolic, anti-catabolic, anti-proteolytic, protein-sparing… these are terms that describe the state of protein affairs in muscle. The bodybuilding community likes to define anabolic compounds as those which increase amino acid shuttling into muscle and increase protein synthesis. Likewise, anti-catabolic, or antiproteolytic (the more specifically correct term) compounds are defined as those which decrease amino acid shuttling out of muscle (also called protein-sparing). Irrespective of whether amino acids are being gained within muscle due to an increase in the influx of amino acids and enhanced protein synthesis, or due to the conservation of amino acids already within muscle, or both, the resulting intramuscular environment is anabolic. This is a really good thing for bodybuilders.
Although most bodybuilding supplements really don’t do much, a few bodybuilding supplements may actually help increase the uptake of amino acids into muscle, and a few other supplements may actually help to conserve amino acids already within muscle. Even better yet, there are a very few supplements that contain formulations of ingredients that do both — they are anabolic and anti-proteolytic, which means even more muscle protein. One of those very few supplements is Myo-Stack — a Blackstone Labs supplement that contains a “cutting-edge” anabolic and anti-proteolytic compound. This product is all about protein…getting it, saving it, and using it to build rock-hard muscle. The active compounds in Myo-Stack signal muscles to grab more amino acids from the bloodstream and then use them to create muscle protein at a faster rate through increased protein synthesis. The compounds in Myo-Stack also tell muscles to hang on to amino acids already within muscle by decreasing muscle-wasting activities within the muscle, creating a protein-sparing metabolism, and thus maintaining an anabolic state during times when normal protein breakdown occurs. In essence, Myo-Stack helps keep hard-earned muscle intact.
Ajuga turkestanica and Myostatin: Another study on the anabolic effects of Ajuga turkestanica was published in 2012 in Chinese Medicine. The researchers were working for PoliNat, a Spanish company that sells plant-based bioactive extracts – including an extract from Ajuga turkestanica. The researchers observed that at a concentration of 1 micromole Ajuga turkestanica ecdysteroids the muscle cells started to make less myostatin. The researchers repeated the experiment and exposed the muscle cells this time to 1 micromole of an anabolic agent. And, lo and behold – the ecdysteroids turned out to be more effect myostatin inhibitors than the anabolic agent (see graph).
The potential for any substance to increase protein synthesis in muscle by-passing secondary effects common with steroid synthetic drugs are attractive approaches for athletes everywhere. The aim of their study was to initially screen a proprietary Ajuga turkestanica extract (ATE), rich in ecdysteroids for early signs of efficacy (increase/ protection of muscle mass) and safety (lack of androgenic activity). Testosterone and other androgenic steroid drugs have been used in the past to increase or maintain muscle mass. These drugs act via the androgen receptors and as such have shown significant side effects that must be carefully evaluated before initiating any therapy. The anabolic effect of ecdysteroids is connected with the acceleration of translocation processes instead of the induction of new RNA synthesis. Ecdysteroids are not likely to act as the classical steroids, via cytoplasmic receptor and regulation of gene transcriptional activity. Ecdysteroids display significant structural differences from anabolic-androgenic steroid hormones, which may explain the different mechanisms of their anabolic action.
Myo-Stack enhances lean mass gains, limits protein breakdown, and accelerates recovery. Utilizing "Ajuga Turkestanica", Myo-Stack is a support product that can be used on it's own, but achieves even greater results when paired with other Blackstone Labs products.